You shouldn't use Provigil When you have ever had an allergic reaction or skin rash whilst getting modafinil or armodafinil (Nuvigil).

It ought to be employed with caution in people with uncontrolled hypertension, unstable angina, or new myocardial infarction.

Other Healthcare Challenges The existence of other professional medical difficulties may well have an affect on the use of this medication. You should definitely inform your medical doctor For those who have any other health-related issues, especially:

While you are taking this medicine, it is especially critical that the Health care Experienced know If you're taking any in the medicines mentioned under. The following interactions are picked on The idea of their possible importance and are not necessarily all-inclusive.

FYCOMPA is a prescription medication utilised by yourself or with other medicines to take care of partial-onset seizures with or without secondarily generalized seizures in those with epilepsy aged four and more mature and with other medicines to deal with Principal generalized tonic-clonic seizures in people with epilepsy aged 12 and more mature. Significant Basic safety Data

The above data is furnished for standard informational and educational uses only. Particular person ideas could vary and formulary facts alterations. Get in touch with the applicable approach supplier for essentially the most present-day information.

anastrozole will increase the degree or outcome of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.

Modafinil might minimize serum concentrations of other medications to the clinically significant extent, which includes the subsequent:

crofelemer improves amounts of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. Crofelemer has the prospective to inhibit CYP3A4 at concentrations predicted during the intestine; not likely to inhibit systemically because minimally absorbed.

A four hundred mg dose of modafinil is beneficial for greater individuals or Individuals who have designed a tolerance to modafinil with lengthy-term use.

Threat of pores and skin reactions (eg SJS, harmful necrolysis, and drug rash with eosinophilia and more information systemic signs); discontinue if rash or other hypersensitivity reactions come about

For shift get the job done sleep problem: Older people and teens seventeen decades of age and older—200 milligrams (mg) one hour before you decide to get started working. Youngsters and youngsters younger than seventeen years of age—Use and dose have to be determined by your doctor. Skipped Dose In case you miss a dose of the drugs, skip the skipped dose and go back to your regular dosing schedule. Never double doses.

Contraindicated (two)modafinil will enhance the level or result of mavacamten by influencing hepatic enzyme CYP2C19 metabolism. Contraindicated. Powerful or reasonable CYP2C19 inhibitors may well increase mavacamten systemic exposure, leading to heart failure resulting from systolic dysfunction.

Minimal (1)modafinil will increase the amount or influence of lansoprazole by impacting hepatic enzyme CYP2C19 metabolism. Minor/Importance Unfamiliar. Net impact on pantoprazole actions unknown as a consequence of opposing outcomes of CYP450 enzymes; check